Study aid only. Verify against current guidelines, primary literature, staging manuals, and prescribing information before clinical use.

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Angiosarcoma — Treatment

First-line Second-line SECOND-LINE Angiosarcoma cutaneous / visceral Localized Advanced — first-line Later-line Curative Wide resection ± RT multimodality Taxane Weekly paclitaxel esp. cutaneous / scalp Anthracycline Doxorubicin EORTC 62012 ↗ TKI Pazopanib PALETTE ↗ Other Gemcitabine-based / checkpoint inhibitor UV-driven, high TMB