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Localized Prostate Cancer — Management by Risk Group
Localized prostate
cancer
by risk group
Low risk
Favorable intermediate
Unfavorable intermediate
High / very-high risk
Preferred
Active surveillance
monitor PSA / MRI / biopsy
Option
Active surveillance
or RT / prostatectomy
Radiation
RT + short-term ADT
4–6 months
Surgery
Radical prostatectomy
+ pelvic LND if indicated
Radiation
RT + long-term ADT ± abiraterone
STAMPEDE ↗
Surgery
Radical prostatectomy + LND
multimodal