Study aid only. Verify against current guidelines, primary literature, staging manuals, and prescribing information before clinical use.

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Glioblastoma — Treatment

Glioblastoma IDH-wildtype Newly diagnosed Maximal safe resection surgery RT + concurrent temozolomide Stupp protocol Adjuvant temozolomide ± tumor-treating fields EF-14 (TTFields) Elderly / poor performance status Hypofractionated RT + temozolomide MGMT-methylated benefits most Temozolomide alone MGMT-methylated Recurrence Re-resection / re-irradiation selected patients Bevacizumab Clinical trial