Study aid only. Verify against current guidelines, primary literature, staging manuals, and prescribing information before clinical use.

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Peripheral T-Cell Lymphoma — Treatment

First-line Second-line SECOND-LINE Peripheral T-cell lymphoma (nodal) Frontline — CD30+ (ALCL) Frontline — CD30-negative Consolidation Relapsed / refractory BV-based Brentuximab + CHP ECHELON-2 ↗ Chemo CHOP / CHOEP anthracycline-based First remission Autologous HSCT in responders HDACi Belinostat / romidepsin single-agent ↗ Antifolate Pralatrexate PROPEL ↗