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Multiple Myeloma — Treatment
First-line
Second-line
SECOND-LINE
Multiple myeloma
(newly diagnosed)
Transplant-eligible
Transplant-ineligible
Relapsed / refractory
Quadruplet
Dara-VRd → autologous SCT
PERSEUS ↗
Maintenance
Lenalidomide maintenance
post-transplant ↗
Triplet
Dara-Rd
MAIA ↗
Triplet
VRd
SWOG S0777 ↗
Triplet
Triplet by prior exposure
POLLUX / CASTOR ↗
BCMA CAR-T
Cilta-cel / ide-cel
CARTITUDE-4 ↗
BiTE
Teclistamab / talquetamab
bispecific ↗