Study aid only. Verify against current guidelines, primary literature, staging manuals, and prescribing information before clinical use.

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Cervical Cancer — Treatment

First-line Second-line SECOND-LINE Cervical cancer Locally advanced Advanced / recurrent · 1L Later-line Definitive Cisplatin chemoRT + brachytherapy GOG 120 ↗ Intensified Add pembrolizumab to chemoRT KEYNOTE-A18 ↗ Chemo+IO Pembrolizumab + chemo ± bev KEYNOTE-826 ↗ Chemo Carbo/paclitaxel + bevacizumab GOG-240 ↗ ADC Tisotumab vedotin innovaTV-301 ↗ IO Pembrolizumab PD-L1+ / MSI-high ↗