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von Willebrand Disease — Management
von Willebrand
disease
(by type)
Type 1 (mild)
Type 2 / 3 or unresponsive
Adjunct
First-line
Desmopressin (DDAVP)
if DDAVP-responsive
Replacement
VWF concentrate
± factor VIII
Mucosal
Tranexamic acid
antifibrinolytic