Study aid only. Verify against current guidelines, primary literature, staging manuals, and prescribing information before clinical use.

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Heparin-Induced Thrombocytopenia (HIT) — Management

First-line Second-line SECOND-LINE Suspected HIT 4T score + platelet drop Immediate After platelet recovery Stop Discontinue ALL heparin including flushes / LMWH Anticoagulate Non-heparin anticoagulant argatroban / bivalirudin / fondaparinux ↗ Avoid No platelet transfusion unless bleeding Transition DOAC or warfarin overlap; treat ≥ 3 months if thrombosis